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The Science behind it

Electrolysed Hypochlorous solution (HOCl) is naturally produced as an extremely effective biocide against pathogens, which was discovered in the 1800s. HOCl works in the body to kill, attenuate or break-down harmful microorganisms by destroying their cell membrane, DNA, RNA and proteins, as well as halting its growth processes. Better yet, your body’s immune cells (neutrophils – white blood cells) naturally produce HOCl as a completely non-toxic broad spectrum biocide which not only enhances cell healing processes but also acts as an anti-inflammatory agent.

 We use ultramodern electrochemical activation processes, in accordance with EPA and ISO standards, to consistently convert pH controlled salt-water solutions into this incredible, highly bioactive and metastable biocide. HOCl as a stand-alone chemical has only recently become commercially available as there have not been affordable alternatives to standard sanitizers/disinfectants, until now. SanOT’s Electrolysed Hypochlorous Solution has come to the market to solve your sanitisation needs.

Modes Of Action

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Anti-pathogenic Effects

HOCl not only directly attacks cell membrane proteins to deactivate and disrupt a microbial cell’s functionality, but it also increases the osmolarity potential across the cell membrane. The result of disrupted membrane proteins and increased osmolarity potential across the microbial cells causes them to rapidly absorb excessive amounts of acidic water and lyse from bursting.

It is a strongly oxidizing and deproteinizing compound that reacts with thiols, proteins, amino acids, DNA, RNA and carbohydrates. Therefore, if a cell is not instantly lysed from contact with HOCl, it becomes non-functional and unable to perform basic cell processes, such as glucose oxidation, DNA replication, RNA synthesis and protein production, eventually causing cell death.

Anti-Inflammatory Effects

Inflammation is caused by the activation of pro-inflammatory factors as a response to mechanical damage or infections. The presence of HOCl has various means and processes of anti-inflammatory actions, to neutralise and reduce inflammation. HOCl can neutralise harmful microbial toxins before they can trigger inflammatory responses in infected cells. HOCl also neutralises and inhibits the messenger proteins (such as NF-κB kinase) that are responsible for recruiting pro-inflammatory factors.

Wound Healing Effects

Whenever an injury occurs, a cascade of complex responses occur to prevent infection, control bleeding and stimulate cellular repair. There are multiple ways in which damaged, dehydrated or non-functional cells are repaired, many of which are initiated or enhanced by the presence of HOCl. One of the first types of cells recruited to a wound site are white blood cells, which secretes HOCl. As a result of the release of HOCl, an increase in the production of cytokines (healing messenger proteins) and growth factors (stimulate cellular division) occurs. Taurine, an amino acid, is also chemically transformed to Taurine Chloramine which is a powerful wound healing factor.  

Modes Of Action

Anti-pathogenic Effects

HOCl not only directly attacks cell membrane proteins to deactivate and disrupt a microbial cell’s functionality, but it also increases the osmolarity potential across the cell membrane. The result of disrupted membrane proteins and increased osmolarity potential across the microbial cells causes them to rapidly absorb excessive amounts of acidic water and lyse from bursting.
 It is a strongly oxidizing and deproteinizing compound that reacts with thiols, proteins, amino acids, DNA, RNA and carbohydrates. Therefore, if a cell is not instantly lysed from contact with HOCl, it becomes non-functional and unable to perform basic cell processes, such as glucose oxidation, DNA replication, RNA synthesis and protein production, eventually causing cell death.  

Anti-Inflammatory Effects

Inflammation is caused by the activation of pro-inflammatory factors as a response to mechanical damage or infections. The presence of HOCl has various means and processes of anti-inflammatory actions, to neutralise and reduce inflammation. HOCl can neutralise harmful microbial toxins before they can trigger inflammatory responses in infected cells. HOCl also neutralises and inhibits the messenger proteins (such as NF-κB kinase) that are responsible for recruiting pro-inflammatory factors.

Wound Healing Effects

Whenever an injury occurs, a cascade of complex responses occur to prevent infection, control bleeding and stimulate cellular repair. There are multiple ways in which damaged, dehydrated or non-functional cells are repaired, many of which are initiated or enhanced by the presence of HOCl. One of the first types of cells recruited to a wound site are white blood cells, which secretes HOCl. As a result of the release of HOCl, an increase in the production of cytokines (healing messenger proteins) and growth factors (stimulate cellular division) occurs. Taurine, an amino acid, is also chemically transformed to Taurine Chloramine which is a powerful wound healing factor.

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